For a project, I am looking for a board to connect eight different neopixel-strips to, on eight different data pins. Because of the great length between the board and the first pixels of these strips, I'd like to have a board that operates on 5V instead of 3.3V. Then, the software that I have written to manage the LEDs is made in (micro)python. Finally, for simplicity's sake, I'd like to run this complete project on a single board without too many external components.
So, I have found 5V boards with enough pins, like the Arduino Mega. I have also found boards with enough pins and support for micropython or circuitpython, like the ESP32 or Arduino Zero.
However, I haven't quite found a board that matches all my requirements. The Arduino Mega doesn't support Python (or does it?) and the ESP32 and Arduino Zero operate at 3.3V, not 5V.
Of course, an ESP32 with a level shifter (as shown on https://github.com/Aircoookie/WLED/wiki) would work, but is there perhaps a board out there that fits all my requirements our of the box?
Edit: It seems I misunderstood some things about the hardware - sorry, I'm a software guy, not really a hardware guy :-) I fixed the question above as not to confuse future readers.