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I'm try to connect my Arduino Mega 2560 to PC, but I think it's not easy as I imagine. I spent a lot's of time to install USB driver. Here is a screenshot:

Device manager

When I try to upload blink example, Arduino IDE throw this error:

Sketch uses 656 bytes (0%) of program storage space. Maximum is 253952 bytes.
Global variables use 9 bytes (0%) of dynamic memory, leaving 8183 bytes for local variables. Maximum is 8192 bytes.
avrdude: ser_open(): can't set com-state for "\\.\COM10"
avrdude: ser_drain(): read error: The handle is invalid."

Screenshot of error

Please help to run one simple example.

I think this screen may help to understand my problem:

COM port selection

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  • Did you reboot your PC after installing drivers? – Dampmaskin Oct 20 '17 at 11:34
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I install driver for this site and everything is working well. driver download: wch.cn/download/CH341SER_EXE.html

I'm recommend to unplug arduino first and install driver, after that plug and enjoy.

Here is a video: https://www.youtube.com/watch?v=FhmG5J-AHrg

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    So - you don't have a genuine Arduino then... Some cheap far-east inferior quality clone... – Majenko♦ Oct 20 '17 at 12:47
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What you can try is:

  • Use another USB port
  • Reopen IDE
  • Reinsert the USB cable
  • Use a different USB cable
  • Prevent using a USB 'box' in between
  • Try a different 2560 (if you have)
  • Restart computer
  • Check if it can be found in the system drivers
  • Reinstall IDE (after deinstall it).

However, as the author already mentioned the real solution is needed for some non-genuine Arduinos:

  • Install the CH driver e.g. at wch.cn/download/CH341SER_EXE.html
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  • I do everything(but not change other arduino) but does not meter, I think USB driver is not install correctly. – Avtandil Kavrelishvili Oct 20 '17 at 11:44
  • In that case the last option should fix it (maybe deinstall IDE first just for certainty) – Michel Keijzers Oct 20 '17 at 11:46
  • ok, I'll try it one more time. but, I think best way to fix this issue is throw arduino into trash – Avtandil Kavrelishvili Oct 20 '17 at 11:52
  • nothing change, IDE can not connect to device. – Avtandil Kavrelishvili Oct 20 '17 at 12:03
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    I'm installing this : wch.cn/download/CH341SER_EXE.html and left only this problem: "Sketch uses 1462 bytes (0%) of program storage space. Maximum is 253952 bytes. Global variables use 9 bytes (0%) of dynamic memory, leaving 8183 bytes for local variables. Maximum is 8192 bytes." – Avtandil Kavrelishvili Oct 20 '17 at 12:27
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I also got the same error. Then I un-plugged my connections and pressed the reset button. Then I uploaded the default blink example to my board. Then it's working fine. Then again I made a connection to the board and it shows the same error again. Now, I un-plugged the GND pin; it's working again. So, in my case there was some thing wrong with my connections.

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